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FDA staff worried about lung risk with Alexza drug

WASHINGTON (Reuters) - Alexza Pharmaceutical's experimental drug for calming down patients with schizophrenia or bipolar disorder can cause severe lung problems, U.S. Food and Drug Administration reviewers said.

In review documents released late on Wednesday, FDA staff said they were unsure whether Adasuve was safe for patients, although it successfully treated their agitation.

"The division remains concerned that the ...

Could acute postpartum blues signal bipolar disorder

NEW YORK (Reuters Health) - Women treated for severe psychiatric conditions including major depression shortly after giving birth were more likely to be diagnosed as bipolar later in life compared to those whose first psychiatric episode happened at any other time, in a new study from Denmark.

Researchers said they didn't know if some postpartum depression or schizophrenia-like episodes were ...

Could acute postpartum blues signal bipolar disorder?

NEW YORK (Reuters Health) - Women treated for severe psychiatric conditions including major depression shortly after giving birth were more likely to be diagnosed as bipolar later in life compared to those whose first psychiatric episode happened at any other time, in a new study from Denmark.

Researchers said they didn't know if some postpartum depression or schizophrenia-like episodes were ...

Antipsychotic drugs tied to diabetes risk in kids

NEW YORK (Reuters Health) - The antipsychotic drugs that are increasingly being used to treat bipolar disorder, autism and other mental disorders in children may come with an increased risk of diabetes, a new study suggests.

Previous research has linked the so-called second-generation antipsychotics to an increased risk of diabetes in adults. And there's been some evidence that the drugs ...

J&J, Lilly drugs found among best for manic episodes

LONDON (Reuters) - Antipsychotics are far more effective than mood stabilizers in tackling acute manic episodes, researchers found, and Eli Lilly's Zyprexa, Johnson & Johnson's Risperdal and generic haloperidol outperform the rest.

In a study published in the Lancet medical journal on Wednesday, researchers from Britain and Italy ranked antipsychotic drugs according to their effectiveness and said that since current ...

Axe taken to Sino-Forest shares

It was a bipolar week for China watchers. First Morgan Stanley says it will invest $50 million in YONG. Then Muddy Waters swings its axe in the direction of TRE.

It was the best of times and the worst of times last week as one

China small cap gets the stamp of approval from Morgan Stanley, and Muddy

Waters pulls ...

Catherine Zeta-Jones' admission that she has bipolar disorder has been welcomed by mental health groups as helping fight the stigma attached to the disease, which afflicts a number of celebrities.

Doctors also emphasize that the Welsh actress, treated following the stress of husband Michael Douglas's recent throat cancer, will likely never be free of it but will learn to ...

Catherine Zeta-Jones treated for bipolar disorder

Actress Catherine Zeta-Jones has checked into a mental health clinic to treat her bipolar disorder after helping her husband Michael Douglas fight against cancer, a publicist said.

"After dealing with the stress of the past year, Catherine made the decision to check into a mental health facility for a brief stay to treat her bipolar II disorder," her representative Cece ...

Bipolar disorder vastly undertreated: study

CHICAGO (Reuters) - Bipolar disorder, a brain disorder that strikes early and can cause lifelong disability, is chronically undertreated in many low-income countries, government researchers reported on Monday.

Their survey of more than 61,000 patients suggests 2.4 percent of the world's population may have some form of the disease, which is marked by bizarre shifts in mood, energy ...

Poor reporting mars 'gold standard' drug trials

NEW YORK (Reuters Health) - Skimpy reporting by medical journals has left German doctors trying to write psychiatric guidelines in a pickle: they don't know what studies to trust.

After reviewing 105 supposedly 'gold standard' drug trials for bipolar disorder, they had to exclude several of them and downgrade even more because critical information was lacking from the reports.

In ...

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